Severe hypertension & hypertensive emergency

Acute organ damage (oedema, ACS, dissection) now; LV hypertrophy, the aorta and secondary causes later.

Echo approach, step by step

In a hypertensive emergency, echo looks for acute organ damage: pulmonary oedema, ischaemia and aortic dissection [26]. In chronic hypertension, it measures LV mass and geometry, diastolic function and the aorta. The ESC suggests it when it will change management [23,26].

  1. LV mass and geometryLVMi, RWT → concentric remodelling or hypertrophy [1,23].
  2. Diastolic functionE/e′, LAVI, TR (HFpEF substrate) [2].
  3. Systolic functionLVEF, GLS [23].
  4. AortaRoot and ascending aorta; flap in the acute setting [9].
  5. CoarctationSuprasternal CW of the descending aorta: high velocity with a diastolic "tail" [25].
  6. Bicuspid aortic valveAssociated with coarctation [25].
  7. Takotsubo patternIn phaeochromocytoma crisis [133].

Causes & echo clues

FindingMeaningAction
Pulmonary oedema with preserved EFHypertensive acute HFNitrates, afterload reduction [12,26]
New RWMAACSACS pathway [138]
Aortic flapDissectionCT angiography, surgery [9]
LVHTarget-organ damageIntensify treatment; regression predicts better outcome [66,67]
CoarctationSecondary hypertensionCT or CMR, ACHD team [25]
Takotsubo patternCatecholamine excessMetanephrines [133]

Clinical pathway to the diagnosis

  1. Confirm BPin both arms, with the correct cuff [26].
  2. Emergency or urgency?Look for acute organ damage: fundoscopy, ECG, troponin, creatinine, urinalysis, neurological examination [26].
  3. EmergencyControlled IV BP lowering with agent and target by organ (fastest in dissection) [9,26].
  4. Secondary causesIn young patients, resistant hypertension or sudden onset: aldosterone and renin, renal imaging, metanephrines, sleep apnoea, coarctation [26].

Clinical pearls & pitfalls

PitfallHypertension + chest pain + inter-arm BP difference → image the aorta before giving antithrombotics [9,203].

Red flags